Publications 2016

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  1. Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model. Studer N, Desharnais L, Beutler M, Brugiroux S, Terrazos MA, Menin L, Schürch CM, McCoy KD, Kuehne SA, Minton NP, Stecher B, Bernier-Latmani R and Hapfelmeier S. Front Cell Infect Microbiol., (December 2016) 20;6:191. DOI:10.3389/fcimb.2016.00191.
  2. CRISPR/Cas9-Based Efficient Genome Editing in Clostridium ljungdahlii, an Autotrophic Gas-Fermenting Bacterium. Huang H, Chai C, Li N, Rowe P, Minton NP, Yang S, Jiang W and Gu Y. ACS Synth Biol(December 2016) 16;5(12):1355-1361. DOI:10.1021/acssynbio.6b00044.
  3. A genetic assay for gene essentiality in Clostridium. Walker DJ, Heap JT, Winzer K and Minton NP. Anaerobe, (December 2016) 42:40-43. DOI:10.1016/j.anaerobe.2016.07.007.
  4. Coinfection and Emergence of Rifamycin Resistance during a Recurrent Clostridium difficile Infection. Stevenson EC, Major GA, Spiller RC, Kuehne SA and Minton NP. J Clin Microbiol(November 2016) 54(11):2689-2694. DOI:10.1128/JCM.01025-16.
  5. A roadmap for gene system development in Clostridium. Minton NP, Ehsaan M, Humphreys CM, Little GT, Baker J, Henstra AM, Liew F, Kelly ML, Sheng L, Schwarz K and Zhang Y. Anaerobe, (October 2016) 41:104-112. DOI:10.1016/j.anaerobe.2016.05.011
  6. What's a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives. Collery MM, Kuehne SA, McBride SM, Kelly ML, Monot M, Cockayne A, Dupuy B, Minton NP. Virulence, (September 2016) 21:1-15. DOI:10.1080/21505594.2016.1237333.
  7. Complete Genome Sequence of Geobacillus thermoglucosidasius NCIMB 11955, the Progenitor of a Bioethanol Production Strain. Sheng L, Zhang Y and Minton NP. Genome Announc, (September 2016) 29:4(5),01065-16. DOI:10.1128/genomeA.01065-16.
  8. Clostridium difficile Genome Editing Using pyrE Alleles. Ehsaan M, Kuehne SA and Minton NP. Methods Mol Biol., (August 2016) 1476:35-52. DOI:10.1007/978-1-4939-6361-4_4.
  9. The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia. Cowardin CA, Buonomo EL, Saleh MM, Wilson MG, Burgess SL, Kuehne SA, Schwan C, Eichhoff AM, Koch-Nolte F, Lyras D, Aktories K, Minton NP, Petri WA Jr. Nat Microbiol., (July 2016) 11;1(8):16108. DOI:10.1038/nmicrobiol.2016.108.
  10. CRISPR-based genome editing and expression control systems in Clostridium acetobutylicum and Clostridium beijerinckii. Li Q, Chen J, Minton NP, Zhang Y, Wen Z, Liu J, Yang H, Zeng Z, Ren X, Yang J, Gu Y, Jiang W, Jiang Y and Yang S. Biotechnol J(July 2016) 11(7):961-72. DOI:10.1002/biot.201600053.
  11. SBRC-Nottingham: sustainable routes to platform chemicals from C1 waste gases. Burbidge A, Minton NP. Biochem Soc Trans., (June 2016) 15;44(3):684-6. DOI:10.1042/BST20160010.
  12. Improving the reproducibility of the NAP1/B1/027 epidemic strain R20291 in the hamster model of infection. Kelly ML, Ng YK, Cartman ST, Collery MM, Cockayne A, Minton NP. Anaerobe(June 2016) 39:51-3. DOI:10.1016/j.anaerobe.2016.02.011.
  13. Production of a functional cell wall-anchored minicellulosome by recombinant Clostridium acetobutylicum ATCC 824. Willson BJ, Kovács K, Wilding-Steele T, Markus R, Winzer K, Minton NP. Biotechnol Biofuels, (May 2016) 23;9:109. DOI:10.1186/s13068-016-0526-x.
  14. Insights into CO2 Fixation Pathway of Clostridium autoethanogenum by Targeted Mutagenesis. Liew F, Henstra AM, Winzer K, Köpke M, Simpson SD, Minton NP. MBio., (May 2016) 24;7(3). DOI:10.1128/mBio.00427-16.
  15. Development of an inducible transposon system for efficient random mutagenesis in Clostridium acetobutylicum. Zhang Y, Xu S, Chai C, Yang S, Jiang W, Minton NP, Gu Y. FEMS Microbiol Lett(April 2016) 363(8). DOI:10.1093/femsle/fnw065.
  16. The dilemma of raising awareness “responsibly”. The need to discuss controversial research with thepublic raises a conundrum for scientists: when is the right time to start public debates? Nerlich B and McLeod C. EMBO Reports, (March 2016) 17:4, 481-485. DOI: 10.15252/embr.201541853.
  17. Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress. Mowday AM, Guise CP, Ackerley DF, Minton NP, Lambin P, Dubois LJ, Theys J, Smaill JB and Patterson AV. Cancers (Basel)(February 2016) 8(7), 63. DOI:10.3390/cancers8070063.
  18. Clostridium difficile-mediated effects on human intestinal epithelia: Modelling host-pathogen interactions in a vertical diffusion chamber. Jafari NV, Kuehne SA, Minton NP, Allan E and Bajaj-Elliott M. Anaerobe, (February 2016) 37:96-102.
  19. Mutant generation by allelic exchange and genome resequencing of the biobutanol organism Clostridium acetobutylicum ATCC 824. Ehsaan M, Kuit W, Zhang Y, Cartman ST, Heap JT, Winzer K, Minton NP. Biotechnol Biofuels, (January 2016) 4;9:4. DOI:10.1186/s13068-015-0410-0


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